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"I think for people with severe depression, they may need to try two or three [different types of antidepressant] before they find one that does work for them, but for most people we can find a medicine which will help them and for whom the benefits will outweigh the risks," she ชุดคอสเพลย์ pantip says. Antidepressants Antidepressants cost the NHS 780,000 per day Between 2005 and 2012, there was a 54% increase in the number of children prescribed antidepressants in the UK Common side-effects include dizziness, headaches and feeling sick. These generally improve with time Antidepressants can cause serotonin syndrome, which - while uncommon - can lead to seizures, an irregular heartbeat and unconsciousness in the most severe cases In rare instances, some people experience suicidal thoughts and a desire to self-harm when they first take antidepressants. People under the age of 25 seem particularly at risk Sources: Health and Social Care Information Centre, World Health Organization, NHS Choices But according to some experts, such as Prof David Healy, the side-effects of antidepressants are not just felt when someone is taking them, but also when they try to reduce the dose or come off the tablets altogether. "There's a large number of people - and it seems to be more women than men - who have great difficulties trying to reduce the dose," he says. "And if they halt the treatment, they can become terribly agitated, they can become suicidal." "When you look at the clinical trials that have been done, the taper phase - the point where the person is trying to come off the drug - is the riskiest period. "That's the point where the person is most likely to commit suicide, or the most likely to do terrible things." Image caption Prof David Healy says some people experience dangerous withdrawal symptoms when coming off antidepressants Gemma - not her real name - says her withdrawal symptoms were so bad that she is now back on the tablets. "I was told I could come off [antidepressants] no problem," she says. "But I was in a mess basically. I reached a point where I could barely function. I was incredibly anxious - I was highly anxious all the time, so I was very panicky, very agitated.

(It also has a social mission to avoid using cotton that has been treated with toxic chemicals known to harm entire communities of farmers in the developing world.) Mockus explains that cotton is a very versatile fiber. It is strong, so it can be made into towels and sheets that will be used, then washed, over and over. It is absorbent and breathable. And it can be knit in various ways to manage heat differently. Flannel, for instance, can be thick and heavy, while pima can be thin and silky. "It's a workhorse fiber," Mockus says. According to Mockus, creating a garment for sleeping is a particularly challenging proposition because your temperature changes over the course of the night. One signal that your body is tired is that you feel a bit cold, but then as you get under your sheets, you warm up. "You want something that is immediately soft and warm to the touch," she says. "But then you want something that is absorbent and breathable so that if you do overheat you won't notice it." Coyuchi's brushed jersey cotton line of pajamas for both men and women (priced between $68 and $198) was designed to do just that. The fabric is extremely soft and not too thick.

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